PhD Position in Viscoelastic Monitoring of Mechano-Adaptive Response of Artificial Cartilage
Catholic University of Leuven
Belgium

 
KU Leuven departments involved: Human Movement Biomechanics Research Group Biomechanics (mech.kuleuven.be/Mechanobiology) Skeletal biology and engineering Physics and Astronomy (https://perswww.kuleuven.be/~u0005780/index.htm) Polymer chemistry and materials

Project

Osteoarthritis (OA) is a highly prevalent and disabling condition in which the normal joint function is impaired. It is a multi-factorial disease that primarily affects the articular cartilage and in which mechanical factors have been reported to be key-factors.

Within an interdisciplinary project, we are laying the fundamentals of a new approach towards treatment of osteoarthritis by developing an innovative multi-scale monitoring platform that will support the development of targeted exercise efforts towards early OA cartilage.

The monitoring involves the implementation of novel measurement approaches for the visco-elastic characterization of cartilage tissue undergoing bioreactor loading as well as the quantification of cell-generated forces in cell-encapsulated hydrogels.   

To this end,we will combine experimental techniques such as optical coherence tomography, piezo-ultrasound and traction force microscopy and complement them with computational algorithms for extracting 2D and 3D maps of the visco-elastic properties and the cellular forces using inverse problem approaches.

In order to perform these tasks, we are looking for a PhD student with background in (bio)mechanical or bio(medical) engineering or physics, who is skilled in setting up experiments involving optical and mechanical methods, interfacing them with data acquisition systems, and who is familiar with the development of mathematical algorithms and their implementation in programs such as Matlab or Python.

Profile

Master inEngineering – (Bio)Mechanics

Master inPhysics

Master inBio(medical)-engineering

orequivalent studies.

In yourletter of interest, please include:

* your cv

* the scorelist of your Bachelor and Master studies

* amotivation with your interest in the topic of the vacancy and why yourbackground is suitable to tackle the challenges

Offer

The PhD student will work in an interdisciplinary teamof researchers with backgrounds in biomedical sciences, biomedical (biomechanical)engineering, physics and chemistry.

Interested?

For moreinformation please contact Prof. dr. Christ Glorieux, tel.: +32 16 32 72 01,mail: christ.glorieux@kuleuven.be or Prof. dr. ir. Hans Van Oosterwyck, tel.: +32 16 32 70 67, mail: hans.vanoosterwyck@kuleuven.be.

You can apply for this job no later than September 30, 2020 via the
KU Leuven seeks to foster an environment where all talents can flourish, regardless of gender, age, cultural background, nationality or impairments. If you have any questions relating to accessibility or support, please contact us at diversiteit.HR@kuleuven.be.
  • Employment percentage: Voltijds
  • Location: Leuven
  • Apply before: September 30, 2020
  • Tags: Natuurkunde en Sterrenkunde


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