Postdoctor in Control of Biopharmaceutical Processes
Royal Institute of Technology School of Electrical Engineering and Computer Science
Sweden

Postdoctor in Control of Biopharmaceutical Processes

KTH , School of Electrical Engineering and Computer Science

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

Job description

The biopharmaceutical industry is a large and profitable field. Bioproduction has evolved from being based on bacterial systems towards production based on mammalian cells in a majority of biological drugs. The production is taking place in intracellular metabolic reaction networks. The legacy is to grow cell cultures in fed-batch bioreactors, but the field is rapidly evolving as a result of new trends and a constantly increasing competition. In this perspective, integrated continuous bioprocessing, i.e. a process consisting of a perfusion cell culture where a medium is steadily added, has received significant attention both from industry and academia. This interest is rapidly increasing and nearly all the large Pharma/Biotech companies are looking into this type of intensified process.

Modeling and control will play a key role in enabling advanced bioprocesses for the production of biopharmaceuticals. Through several projects, we are building a sustainable world-class environment for modeling and control of intracellular networks and cell cultures for bioproduction. Currently, the team involves two Full Professors with specializations in data-driven modeling and control, two postdocs, and one Ph.D student. We are recruiting new members to the group.

This advertised postdoc position is part of the EU project iConsensus with the objective to develop new on-line and at-line sensors and use these to optimize and control cell cultures and their products. The project, led by KTH, involves several leading European biopharmaceutical companies and universities. The postdoc position will also be associated with the Centre for Advanced Bioproduction (AdBIOPRO), led by KTH, and in collaboration with Lund University and Karolinska University Hospital as well as seven Swedish companies in the Biopharmaceutical/Biotech industry, including GE Healthcare. The Centre focuses on bioproduction based on mammalian cells, with the objective to respond to the paradigm shift towards continuous processing and to become world-leading.

This project concerns optimization and model-based control of intracellular networks and cell cultures by manipulating culture media and other process parameters. It involves developing methodologies for optimizing cell metabolism through media feeds, and advanced model-based feedback control based on newly developed models and on-line and at-line sensors. The project is in close collaboration with the School of Chemistry, Biotechnology and Health at KTH, world-leading in continuous bioprocessing and hosting extensive laboratory facilities, and our industrial partners, with the ultimate objective to verify methodologies in an industrial setting.

For the successful candidate, the project provides an excellent starting point for a career in a rapidly evolving field.

What we offer

  • A position at a leading technical university that generates knowledge and skills for a sustainable future
  • Engaged and ambitious colleagues along with a creative, international and dynamic working environment
  • Works in Stockholm, in close proximity to nature
  • Help to relocate and be settled in Sweden and at KTH

Read more about what it is like to work at KTH

Qualifications

Requirements

A doctoral degree or an equivalent foreign degree, in Electrical Engineering, Chemical Engineering or Biotechnology. The doctoral degree must have been obtained within the last three years prior to the application deadline (with some exceptions for special reasons such as periods of sick or parental leave, kindly indicate if such reason exists in your resume).

The candidate should have a strong background in at least one of the areas; biosystems modeling, model-based control or optimization, and experience from at least one more of these areas.

There are high requirements on outstanding research and publication record. Well-developed analytical and problem-solving skills are also required. We are looking for a strongly motivated person, who can work both independently and in collaboration with others. Good command of English orally and in writing is required to present and publish research results.

Great emphasis will be placed on personal competency

Trade union representatives

You will find contact information to trade union representatives on KTH's webbpage.

Application

The application should include:

  1. Full curriculum vitae including your relevant academic, professional, and other achievements, experience, and knowledge.
  2. Copy of the degree certificate(s) from your previously attended university-level institutions, with certified translations in English (unless provided so by the issuing institution)
  3. Statement of purpose: What are your academic interests, how does the project relate to your previous studies and future goals; maximum 2 pages long
  4. List of publications and copies of two representative publications or technical reports no longer than 10 pages each. For longer documents (e.g. theses), please provide a summary (abstract) and a web link to the full text
  5. Letters of recommendation
  6. Contact information for two reference persons

Log into KTH's recruitment system to apply for this position. You are the main responsible to ensure that your application is complete according to the ad.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

About the employment

The offered position is time-limited to 1 year with the possibility of extension with 1 more year.

A position as a postdoctoral fellow is a time-limited qualified appointment focusing mainly on research, intended as a first career step after a dissertation.

Others

Striving towards gender equality, diversity and equal conditions is both a question of quality for KTH and a given part of our values.

For information about processing of personal data in the recruitment process please read here.

We firmly decline all contact with staffing and recruitment agencies and job ad salespersons.

Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment Prefereably as soon as possible, or according to agreement
Salary Monthly
Number of positions 1
Working hours 100%
City Stockholm
County Stockholms län
Country Sweden
Reference number J-2020-2796
Contact
Prof. Elling Jacobsen, jacobsen@kth.se
Felicia Gustafsson, HR, rekrytering@eecs.kth.se
Published 08.Dec.2020
Last application date 15.Jan.2021 11:59 PM CET

 


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